| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Hernandez, N, 2003-09-11 07:42:29,
Edited: Joshi-Tope, G, 0000-00-00 00:00:00,
There are three basic types of RNA polymerase III promoters. The three types of RNA polymerase III promoters are known as type 1, type 2, and type 3 promoters. Type 1 promoters are found in the 5S genes and consist of a gene-internal element called the internal control region (ICR), that is subdivided into A block, intermediate element, and C block (Bogenhagen, 1985; Sakonju et al., 1980). Type 2 promoters are found in tRNA genes, Adenovirus 2 VAI gene, and other genes (Galli et al., 1981; Sharp et al., 1981). These promoters consists of two gene-internal elements called the A and the B boxes. Type 3 promoters consist of a distal sequence element (DSE) that serves as an enhancer, a proximal sequence element (PSE), and a TATA box (Baer et al., 1989; Lobo and Hernandez, 1989). <p>Some promoters combine elements from type 2 and 3 promoters. For example, the <i>S. cerevisiae</i> U6 promoter, also shown in the figure, contains the TATA box typical of type 3 promoters and the A and B boxes typical of type 2 promoters. Moreover, in <i>S. pombe</i>, nearly all tRNA and 5S genes contain a TATA box in addition to gene-internal elements, and the TATA box is required for transcription. Ã?Â
|
| biopax3:xref |
http://identifiers.org/pubmed/2308839,
http://identifiers.org/pubmed/2752422,
http://identifiers.org/pubmed/6947245,
http://identifiers.org/pubmed/7312050,
http://identifiers.org/pubmed/7357599,
http://identifiers.org/pubmed/7357604,
urn:biopax:UnificationXref:REACTOME DATABASE ID_76046,
urn:biopax:UnificationXref:REACTOME_REACT_281_2
|
| biopax3:dataSource | |
| biopax3:displayName |
RNA Polymerase III Transcription Initiation
|
| biopax3:organism | |
| biopax3:pathwayComponent | |
| biopax3:pathwayOrder |