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Authored: Gillespie, ME, 2004-08-10 16:59:18,
Edited: Gillespie, ME, 0000-00-00 00:00:00,
Reviewed: Vaux, D, 0000-00-00 00:00:00,
The death receptors, all cell-surface receptors, begin the process of caspase activation. The common feature of these type 1 transmembrane proteins is the "death-domain" a conserved cytoplasmic motif found on all of the three receptors (FAS/CD95, TNF-receptor, and TRAIL-receptor) that binds the Fas-associated protein with death domain (FADD)
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Death Receptor Signalling
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