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Authored: D'Eustachio, P, 2004-08-24 14:00:00, TFPI binds to the factor VIIa:TF complex and to factor Xa at the endothelial surface, forming a stable heterotetrameric complex in which factor VIIa is catalytically inactive.
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Inactivation of factor VIIa by TFPI
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TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa
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