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Authored: Akkerman, JW, 2009-06-03, Edited: Jupe, S, 2010-06-07, Reviewed: Kunapuli, SP, 2010-06-07, TRPC3, 6 and 7 are non-selective cation channels that are activated by diacylglycerol (DAG) independently of protein kinase C activation by DAG. By analogy with the structures of voltage-regulated calcium channels, TRPC channels are probably tetramers of TRPC protein; heterotetramers within the 3/6/7 group have been observed.
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DAG activation of TRPC channels
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