Source:http://www.reactome.org/biopax/48887BiochemicalReaction958
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Authored: Akkerman, JW, 2009-06-03,
Edited: Jupe, S, 2010-09-01,
Reviewed: Heemskerk, JW, 2010-09-01,
Thrombin binds to the GP1b-IX-V receptor during platelet aggregation. This leads to increased PAR activation, possibly due to favourable orientation of thrombin towards the PAR extracellular domain.
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Thrombin binding to GP1b:IX:V
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