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3-phosphoinositide dependent protein kinase-1 (PDK1, also known as PKB kinase because of its activity at Protein kinase B) phosphorylates T410 of Protein kinase C zeta type (PKC zeta), leading to activation. The motif surrounding T410 is highly conserved in other PKC family members suggesting that PDK1 might activate other PKCs., Authored: Akkerman, JW, 2009-09-04, Edited: Jupe, S, 2009-11-03, Reviewed: Harper, MT, 2009-11-02, Reviewed: Jones, ML, 2009-11-02, Reviewed: Poole, AW, 2009-11-02
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PDK1 activates PKC zeta
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