Statements in which the resource exists as a subject.
PredicateObject
rdf:type
biopax3:comment
Authored: Akkerman, JW, 2009-09-04, Edited: Jupe, S, 2009-11-03, Reviewed: Harper, MT, 2009-11-02, Reviewed: Jones, ML, 2009-11-02, Reviewed: Poole, AW, 2009-11-02, Vav interacts directly with PIP2 and PIP3, with a fivefold selectivity for PIP3 over PIP2. PIP3 gives a twofold stimulation of Vav1 GEF activity while PIP2 leads to 90% inhibition. Binding probably occurs through the PH domain, known to bind phosphoinositides.
biopax3:xref
biopax3:dataSource
biopax3:displayName
PIP2 inhibits Vav
biopax3:left
biopax3:right