Source:http://www.reactome.org/biopax/48887BiochemicalReaction847
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Akkerman, JW, 2009-06-03,
Edited: Jupe, S, 2010-06-07,
Reviewed: Kunapuli, SP, 2010-06-07,
The classical view of G-protein signalling is that the G-protein alpha subunit dissociates from the beta:gamma dimer. Activated G alpha (s) and the beta:gamma dimer then participate in separate signaling cascades. Although G protein dissociation has been contested (e.g. Bassi et al. 1996), recent in vivo experiments have demonstrated that dissociation does occur, though possibly not to completion (Lambert 2008).
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
Dissociation of the Prostacyclin receptor:Gs complex
|
| biopax3:left | |
| biopax3:right |