| http://www.reactome.org/bio... | rdf:type | biopax3:BiochemicalReaction | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Reviewed: Ranganathan, S, 2007-11-23 00:10:26 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Farnesyltransferase/geranyl-geranyltransferase catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. This enzyme complex consists of a heterodimer of an alpha and a beta subunit. The alpha subunit is thought to function in the formation of a stable complex with the substrate. This alpha subnit is cleaved by caspase 3. Expression of the cleavage product (60-379) induces cell death (Kim et al., 2001). | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Edited: Matthews, L, 2007-10-09 13:44:38 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Edited: Matthews, L, 2007-11-11 23:40:56 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Edited: Matthews, L, 2007-09-03 07:38:20 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:comment | Authored: Schulze-Osthoff, K, 2007-09-03 07:52:18 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | http://identifiers.org/pubm... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:xref | urn:biopax:UnificationXref:... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:dataSource | urn:biopax:Provenance:react... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:dataSource | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:displayName | Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:eCNumber | 3.4.22 | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:left | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:right | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:right | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:stepProcess | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:controlled | http://www.reactome.org/bio... | lld:biopax3 |
| http://www.reactome.org/bio... | biopax3:pathwayComponent | http://www.reactome.org/bio... | lld:biopax3 |
