Source:http://www.reactome.org/biopax/48887BiochemicalReaction796
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Authored: Schulze-Osthoff, K, 2008-05-18 10:00:05,
Edited: Matthews, L, 2008-06-02 07:49:06,
Following iinduction of apoptosis in epithelial cells, tight junction are disrupted. Tight junction proteins, including the the transmembrane protein occludin and the cytoplasmic adaptor proteins ZO-1 and ZO-2 are fragmented by caspase cleavage (Bojarski et al., 2004).,
Reviewed: Ranganathan, S, 2008-06-11 19:13:33
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Caspase-mediated cleavage of occludin
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3.4.22
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