Source:http://www.reactome.org/biopax/48887BiochemicalReaction788
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biopax3:comment |
Apoptosis-induced cleavage of beta-catenin by caspase 3 results in reduced alpha catenin binding, relocalization to the cytoplasm and a reduction in cell-cell contact. In addition, the resulting proteolytic fragments have reduced transcription factor activity (Steinhusen et al., 2000 ).,
Authored: Schulze-Osthoff, K, 2007-09-03 07:52:18,
Edited: Matthews, L, 2007-10-09 13:44:38,
Edited: Matthews, L, 2007-11-11 23:40:56,
Reviewed: Ranganathan, S, 2008-06-11 19:13:33
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biopax3:displayName |
Caspase mediated cleavage of beta-catenin
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biopax3:eCNumber |
3.4.22
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biopax3:right |