Source:http://www.reactome.org/biopax/48887BiochemicalReaction783
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Schulze-Osthoff, K, 2008-05-18 10:00:05,
Edited: Matthews, L, 2007-09-03 07:38:20,
Edited: Matthews, L, 2008-05-18 15:44:16,
Reviewed: Ranganathan, S, 2008-06-11 19:13:33,
Vimentin is cleaved by several caspases during apoptosis (Morishima et al., 1999, Byun et al., 2001). This clevage disrupts the cytoplasmic network of intermediate filaments and coincides temporally with nuclear fragmentation. Caspase-6 recognizes and cleaves C terminal side of Asp-429.
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
Caspase-mediated cleavage of vimentin at TNLD (429)
|
| biopax3:eCNumber |
3.4.22
|
| biopax3:left | |
| biopax3:right |