Source:http://www.reactome.org/biopax/48887BiochemicalReaction78
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Authored: Orlic-Milacic, M, 2012-04-04,
Edited: Jassal, B, 2012-04-10,
Knocking down WWTR1 (TAZ) expression by siRNA treatment inhibits TGF-beta-dependent transcription of SMAD7 in human hepatocellular carcinoma cell line Hep G2. Chromatin immunoprecipitation (ChIP) confirmed binding of both WWTR1 and SMAD2/3 to the promoter of SMAD7 gene in response to TGF-beta stimulation (Varelas et al. 2008).,
Reviewed: Huang, Tao, 2012-05-14
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WWTR1:SMAD stimulates transcription of SMAD7
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