Source:http://www.reactome.org/biopax/48887BiochemicalReaction749
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Authored: Gopinathrao, G, 2004-08-18 11:49:08,
It is thought that due to its p53 dependence for expression, PUMA could function as a mediator of p53-induced apoptosis. Newly synthesized PUMA protein translocates to mitochondria and binds to BCL-2 and Bcl-X(L) through a BH3 domain.,
Reviewed: Vaux, D, 0000-00-00 00:00:00
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Translocation of PUMA protein to mitochondria
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