Source:http://www.reactome.org/biopax/48887BiochemicalReaction658
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Authored: Lee, KS, 2004-12-08 21:18:23,
During the early stages of mitosis, mitotic kinases including Cdc2 and PLK1 promote reorganization of pericentriolar stacks of Golgi cisternae by phosphorylating GRASP65 (Golgi REasembly Stacking Protein of 65 kDa). Cdc2-Cyclin B1 phosphorylates GRASP65 at the time of mitotic entry,a step that promotes the interaction between GRASP65 and the polo-box domain of PLK1 and the subsequent PLK1-dependent GRASP65 phosphorylation.,
Edited: Gillespie, ME, 0000-00-00 00:00:00
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Activation of the Anaphase Promoting Complex (APC) by PLK1
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