Source:http://www.reactome.org/biopax/48887BiochemicalReaction607
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Authored: Jassal, B, 2010-08-26,
Edited: Jassal, B, 2010-08-26,
Reviewed: He, L, 2010-11-15,
The potassium-transporting ATPase heterodimer catalyzes the hydrolysis of ATP coupled with the exchange of H+ and K+ ions across the plasma membrane. It is composed of alpha and beta chains. Two human genes encode the catalytic alpha subunit, ATP4A and ATP12A (Maeda et al, 1990; Grishin et al, 1994). ATP4A is responsible for acid production in the stomach. <br>ATP12A is responsible for potassium absorption in various tissues. One human gene encodes the beta subunit, ATP4B (Ma et al, 1991).
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The K+-transporting ATPase mediates the exchange of potassium and hydrogen ions
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3.6.3.10
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