Source:http://www.reactome.org/biopax/48887BiochemicalReaction548
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Authored: Jassal, B, 2010-05-17,
Edited: Jassal, B, 2010-05-17,
Reviewed: He, L, 2010-05-10,
The human gene SLC35D2 encodes the UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter (UGTREL8; homolog of Fringe connection protein 1, HFRC1). It resides on the Golgi membrane where it mediates the antiport of nucleotide sugars such as UDP-GlcNAc and UDP-glucose into the Golgi lumen in exchange for UMP (Suda T et al, 2004; Ishida N et al, 2005).
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SLC35D2 mediates the antiport of UDP-sugars in exchange for UMP
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