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Authored: Mahajan, SS, 2011-05-22, Edited: Mahajan, SS, 2011-05-23, Reviewed: Jassal, B, 2010-09-23, THIK subfamily has 2 members, THIK1 and THIK 2. THIK 1 forms functional homodimers whereas THIK2 function has not been demonstrated. THIK1 channels are inhibited by halothane. THICK1 channels form K+ leak channels and are not regulated by acidity or alkalanity changes.
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Activation of THIK
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