Source:http://www.reactome.org/biopax/48887BiochemicalReaction5377
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Authored: Mahajan, SS, 2011-05-18,
Edited: Mahajan, SS, 2011-05-23,
In neuroendocrine cells such as pancreatic alpha-, beta-, and delta-cells and in the brain, ATP sensitive K+ channels assemble as octamers of four Kir 6.1, 6.2 subunits and four high-affinity sulfonyl urea receptor 1 subunits (SUR1). These channels are blocked by excess intracellular levels of ATP. When the ATP is low, ATP dissociates and the channel opens to allow K+ efflux.,
Reviewed: Jassal, B, 2010-09-23
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Activation of ATP sensitive Potassium channels in neuroendocrine cells
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