Source:http://www.reactome.org/biopax/48887BiochemicalReaction5345
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Authored: Mahajan, SS, 2009-09-29,
Edited: Gillespie, ME, 2009-06-02 00:56:21,
Membrane depolarization occurs due to glutamate dependent activation of Ca-impermeable AMPA receptors, which permit the influx of Na+ ions. The depolarization triggers the removal of Mg2+ from the NMDA receptor pore to facilitate its activation. Therefore activation of AMPA receptors by glutamate precedes activation of NMDA receptors.,
Reviewed: Tukey, D, 2009-11-17
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Membrane depolarization upon activation of Ca impermeable AMPA receptors
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