Source:http://www.reactome.org/biopax/48887BiochemicalReaction5281
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Authored: May, B, 2011-03-24,
Carbonic anhydrase VI (CA6) hydrates carbon dioxide to yield bicarbonate and a proton (Thatcher et al. 1998, Nishimori et al. 2007).Carbonic anhydrase deprotonates water to yield a zinc-hydroxyl group and a proton which is transferred to external buffer molecules via histidine or glutamate residues in carbonic anhydrase. The hydroxyl group reacts with carbon dioxide in the active site to yield bicarbonate. A water molecule displaces the bicarbonate and the reaction cycle begins again (reviewed in Lindskog 1997). Depending on the concentrations of reactants the reaction is reversible. CA6 is a major protein of saliva and is also known as gustin.,
Edited: May, B, 2011-03-24,
Reviewed: Jassal, B, 2012-05-16,
Reviewed: Silverman, DN, 2012-05-16
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H2O + CO2 -> H+ + HCO3-
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Carbonic Anhydrase VI Hydrates Carbon Dioxide to Form a Proton and Bicarbonate
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4.2.1.1
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