Source:http://www.reactome.org/biopax/48887BiochemicalReaction5265
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Authored: D'Eustachio, P, 2012-03-14,
Edited: D'Eustachio, P, 2012-03-16,
Organic cation transporters 1 (OCT1, SLC22A1), 2 (OCT2, SLC22A2) and 3 (OCT3, SLC22A3) associated with the plasma membrane all mediate the influx of abacavir. The three transporters have similar affinities for abacavir (Minuesa et al. 2009) but differ in the tissues in which they are expressed and in their distributions on the surfaces of polarized cells (reviewed by Klaasen and Aleksunes 2010).,
Reviewed: Jassal, B, 2012-03-16
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abacavir [extracellular] => abacavir [cytosol]
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OCT (organic cation transporter)-mediated abacavir uptake
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