Source:http://www.reactome.org/biopax/48887BiochemicalReaction5230
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Authored: Jassal, B, 2005-02-09 10:26:12,
N-acetylation occurs in two sequential steps via a <i>ping-pong Bi-Bi mechanism</i>. In the first step, the acetyl group from acetyl-CoA is transferred to a conserved cysteine residue (position 68) in the active site of NAT, with consequent release of coenzyme-A. In the second step, the acetyl group is transferred to the acceptor substrate and the enzyme returns to its initial state.,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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The acetyl group from acetyl-CoA is transferred to the NAT2
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