Source:http://www.reactome.org/biopax/48887BiochemicalReaction5192
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Authored: Jassal, B, 2008-05-19 12:57:01,
Edited: Jassal, B, 2008-05-19 12:57:01,
Long-chain 3-hydroxy fatty acids (3-OHFAs) are omega-hydroxylated to form 3-hydroxydicarboxylic acid (3-OHDCAs) precursors in human liver. These products may be implicated in pathological states where fatty acid mobilzation or impairment of mitochondrial fatty acid beta-oxidation increases 3-OHFA levels. CYP4A11, an orphan P450, has been shown to omega-hydroxylate 3-hydroxystearate and 3-hydroxypalmitate; the latter is shown here.,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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CYP4F11 omega-hydroxylates 3-hydroxypalmitate
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