Source:http://www.reactome.org/biopax/48887BiochemicalReaction5191
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Authored: Jassal, B, 2008-05-19 12:57:01,
CYP3A43 belongs to the CYP3A family, of which CYP3A4 is the most active member in the biotransformation of xenobiotics. Testosterone metabolites are a major determinant of prostate growth and differentiation. CYP3A43, which is expressed in the prostate, exhibits minor 6-beta-hydroxylation activity towards testosterone. Thus, CYP3A43 may be involved in the etiology of prostate cancer.,
Edited: Jassal, B, 2008-05-19 12:57:01,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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CYP3A43 catalyzes the 6beta-hydroxylation of testosterone
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