Source:http://www.reactome.org/biopax/48887BiochemicalReaction5185
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Authored: Jassal, B, 2008-05-19 12:57:01,
Edited: Jassal, B, 2008-05-19 12:57:01,
Retinoic acid (RA) is a biologically active analogue of vitamin A (retinol). RA plays an important role in regulating cell growth and differentiation.CYP26A1 is involved in the metabolic breakdown of RA by 4-hydroxylation. CYP26A1-mediated 4-hydroxylation is specific for all-trans-RA but not for the isomers 13-cis-RA and 9-cis-RA.,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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CYP26A1 breaks down all-trans-retinoic acid by 4-hydroxylation
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