Source:http://www.reactome.org/biopax/48887BiochemicalReaction5176
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Authored: Jassal, B, 2008-05-19 12:57:01,
Dodecanoic acid (Lauric acid) is a medium-chain fatty acid which serves as a model substrate for studying the CYP4A gene subfamily of cytochrome P450s. CYP4A11 and CYP2E1 are the principal isozymes involved in omega-hydroxylation and omega-1 hydroxylation respectively of dodecanoic acid.,
Edited: Jassal, B, 2008-05-19 12:57:01,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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CYP4A11 omega-hydroxylates laurate
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dodecanoic acid + O<sub>2</sub> + NADPH + H<sup>+</sup> -> 12-hydroxydodecanoic acid + H<sub>2</sub>O + NADP<sup>+</sup>
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