Source:http://www.reactome.org/biopax/48887BiochemicalReaction5159
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Authored: Jassal, B, 2008-05-19 12:57:01,
Edited: Jassal, B, 2008-05-19 12:57:01,
Paclitaxel (Taxol) is a naturally occurring member of the taxane family of antitumor drugs. It acts by stabilizing microtubules. Paclitaxel is inactivated in human liver by CYP2C8, which catalyzes 6alpha-hydroxylation of paclitaxel.,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation
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