Source:http://www.reactome.org/biopax/48887BiochemicalReaction5087
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Authored: Jassal, B, 2008-10-01 13:18:42,
Edited: Jassal, B, 2008-01-08 13:51:41,
Iodide (I-) is transported from blood serum into the thyroid cell by the Na+/I- symporter (sodium/iodide). This intrinsic membrane protein uses energy from the inward movement of Na+ to drive the process and accumulate I- in the cell, maintaining a cellular concentration 30-40 times that of the serum concentration. This process, also called the iodide trap, is stimulated by TSH (thyroid stimulating hormone) and is saturable by large amounts of I-.,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54
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Iodide is taken up by thyroid epithelial cells
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