Source:http://www.reactome.org/biopax/48887BiochemicalReaction5078
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Gopinathrao, G, 2008-05-19 18:50:15,
Reviewed: D'Eustachio, P, 2008-06-12 17:57:32,
The rapid turnover of ODC is brought about by the 26S proteasome. Proteolytic processing of ODC is highly unusual in that ubiquitination is not required for this degradation. Instead, a non-covalent association with antizyme directs ODC to the proteasome. Antizyme increases the degradation of ODC by enhancing its interaction with the proteasome (Pegg, 2006).
|
| biopax3:xref |
http://identifiers.org/pubmed/11265248,
http://identifiers.org/pubmed/12660156,
http://identifiers.org/pubmed/16205122,
http://identifiers.org/pubmed/16223706,
http://identifiers.org/pubmed/16459331,
http://identifiers.org/pubmed/7864793,
urn:biopax:UnificationXref:REACTOME DATABASE ID_353125,
urn:biopax:UnificationXref:REACTOME_REACT_13491_1
|
| biopax3:dataSource | |
| biopax3:displayName |
26S proteosome degrades ODC holoenzyme complex
|
| biopax3:left | |
| biopax3:right |