Source:http://www.reactome.org/biopax/48887BiochemicalReaction5070
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Authored: Stephan, R, 2010-10-24,
Edited: Jassal, B, 2011-03-30,
MTA phosphorylase catalyzes the cleavage of adenine from S-methylthioadenosine (MTA) and subsequent phosphorylation of the product, yielding 5'-methylthio ribose-1-phosphate (Kamatani et al. 1981). The active form of the enzyme is a homotrimer (Della Ragione et al. 1985). Mutations in the gene are associated with a rare bone dysplasia and cancer syndrome, DMS-MFH (Camacho-Vanegas et al. 2012).,
Reviewed: D'Eustachio, P, 2011-05-23
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MTA is cleaved and phosphorylated
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2.4.2.28
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