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Authored: D'Eustachio, P, 2007-07-18 14:33:15, Cytosolic creatine kinase catalyzes the reaction of creatine and ATP to form phosphocreatine and ADP. The active form of the enzyme is a dimer. Monomers of the cytosolic enzyme occur in two isoforms, B and M, so called because of their abundance in brain and muscle respectively. The enzyme is widely expressed in the body and many tissues express both isoforms. Both homo- (BB, MM) and heterodimers (BM) are catalytically active.
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creatine + ATP => phosphocreatine + ADP [CKB,CKM]
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2.7.3.2
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