Source:http://www.reactome.org/biopax/48887BiochemicalReaction503
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Authored: Mahajan, SS, 2008-10-17 21:22:50,
Edited: Gillespie, ME, 2009-11-19,
Reviewed: Restituito, S, 2008-11-27 12:38:49,
The human gene SLC6A4 encodes the sodium-dependent serotonin transporter 5HTT which mediates the re-uptake of serotonin from the synaptic cleft thus terminating the action of serotonin (Canli T and Lesch KP, 2007). The serotonin taken up in the cytosol from the synaptic cleft may be recycled into synaptic vesicles or metabolized.
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Reuptake of serotonin from the synapse
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