Source:http://www.reactome.org/biopax/48887BiochemicalReaction502
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Authored: Mahajan, SS, 2008-06-26 19:01:12,
Edited: Gillespie, ME, 2009-11-19,
Reviewed: Restituito, S, 2008-11-27 12:38:49,
The human gene SLC6A3 encodes the sodium-dependent dopamine transporter, DAT which mediates the re-uptake of dopamine from the synaptic cleft (Vandenbergh DJ et al, 2000). Dopamine can then be degraded by either COMT or monoamine oxidase.
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Reuptake of dopamine from the synaptic cleft into neurons
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Reuptake of dopamine from the synaptic celft into neurons
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