Source:http://www.reactome.org/biopax/48887BiochemicalReaction4975
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Cytosolic glutamine synthetase (glutamate-ammonia ligase - GLUL) catalyzes the reaction of glutamate, ammonia, and ATP to form glutamine, ADP, and orthophosphate. The enzyme is a decamer (Krajewski et al. 2008). Mutations in the gene encoding GLUL cause glutamine deficiency in vivo (Haberle et al. 2005).
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glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]
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6.3.1.2,
mate-ammonia
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