Source:http://www.reactome.org/biopax/48887BiochemicalReaction4827
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Cytosolic 5'3'-nucleotidase (NT5C) catalyzes the hydrolysis of deoxy- and ribo- guanosine and inosine nucleoside monophosphates to yield the corresponding nucleosides and orthophosphate. The active form of the enzyme is a homodimer, with an absolute requirement for Mg++ (Hoglund and Reichard 1990; Rampazzo et al. 2000). This enzyme appears to play a central role in the "substrate cycles" that regulate cytosolic deoxynucleotide levels (Gazziola et al. 2001).
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
(d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate [NT5C]
|
| biopax3:eCNumber |
3.1.3.5
|
| biopax3:left | |
| biopax3:right |