Source:http://www.reactome.org/biopax/48887BiochemicalReaction4826
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| biopax3:comment |
Cytosolic 5'-nucleotidase IA catalyzes the hydrolysis of purine ribo- and deoxyribonucleoside monophosphates to nucleosides plus orthophosphate. The enzyme is allosterically activated by ADP (Hunsucker et al. 2001). The human enzyme is inferred to be a homotetramer with one Mg++ ion bound per subunit, based on its similarity to the pigeon heart enzyme (Bianchi and Spychala 2003; Sala-Newby et al. 1999; Skladanowski and Newby 1990).
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| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
(2'-deoxy)purine nucleoside 5'-monophosphate + H2O => (2'-deoxy)purine nucleoside + orthophosphate [NT5C1A]
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| biopax3:name |
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate [NT5C1A]
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| biopax3:eCNumber |
3.1.3.5
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