Source:http://www.reactome.org/biopax/48887BiochemicalReaction4810
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Authored: D'Eustachio, P, 2004-02-19 09:47:00,
Edited: D'Eustachio, P, 0000-00-00 00:00:00,
Two isoforms of adenylosuccinate synthetase, ADSS and ADSSL1, catalyze the reaction of IMP, aspartate, and GTP to form adenylosuccinate, GDP, and orthophosphate (Powell et al. 1992; Sun et al. 2005). ADSS is a homotetramer (unpublished crystallographic data - PDB 2V40) and ADSSL1 is inferred to be a tetramer likewise.
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IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS]
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inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate
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6.3.4.4
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