Source:http://www.reactome.org/biopax/48887BiochemicalReaction4644
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| biopax3:comment |
Alpha-linoloyl-CoA is converted to Stearidonoyl-CoA (SDA, 6,9,12,15-18:3(n-3)) by delta-6-destaurase (fatty acid desaturase-2, FADS2). FADS2 uses the cytochrome b5 system to add a double bond at position 6. This is the rate limiting step in alpha-linolenic acid (ALA) metabolism (Horrobin 1993).,
Authored: Garapati, P V, 2012-01-11,
Edited: Garapati, P V, 2012-01-11
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| biopax3:xref |
http://identifiers.org/pubmed/11988075,
http://identifiers.org/pubmed/12562861,
http://identifiers.org/pubmed/12713571,
http://identifiers.org/pubmed/1346092,
http://identifiers.org/pubmed/19056654,
http://identifiers.org/pubmed/8386433,
urn:biopax:UnificationXref:REACTOME DATABASE ID_2046084,
urn:biopax:UnificationXref:REACTOME_REACT_121240_1
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| biopax3:dataSource | |
| biopax3:displayName |
Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA
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| biopax3:eCNumber |
1.14.19.3
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