Source:http://www.reactome.org/biopax/48887BiochemicalReaction4629
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Authored: Jassal, B, 2011-09-21,
Edited: Jassal, B, 2011-09-21,
Reviewed: Stephan, R, 2011-10-31,
The mammalian brain-specific, Mg2+-dependent, neutral sphingomyelin phosphodiesterases 2 (Tomiuk et al. 1998, Hofmann et al. 2000) and 3 (Marchesini et al. 2003) (SMPD2 and 3) hydrolyse sphingomyelin (SPHM) to ceramide (CERA) at the plasma membrane.
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Sphingomyelin phosphodiesterase 2 and 3 (SMPD2 and 3) hydrolyse sphingomyelin to ceramide (plasma membrane)
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3.1.4.12
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