Source:http://www.reactome.org/biopax/48887BiochemicalReaction4615
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Authored: D'Eustachio, P, 2009-08-20,
Edited: D'Eustachio, P, 2009-08-20,
Reviewed: Hannun, YA, Luberto, C, 2009-11-18,
Reviewed: Jassal, B, 2009-08-20,
SGPP1 and 2 (sphingosine-1-phosphate phosphatase 1 and 2) enzymes associated with the endoplasmic reticulum membrane catalyze the hydrolysis of cytosolic sphingosine 1-phosphate to form sphingosine and orthophosphate (Johnson et al. 2003; Ogawa et al. 2003).
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sphingosine 1-phosphate + H2O => sphingosine + orthophosphate [cytosolic - SGPP]
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