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ACER1 (alkaline ceramidase 1), associated with the endoplasmic reticulum membrane, catalyzes the reversible hydrolysis of ceramide to yield a free fatty acid (annotated here as stearate) and sphingosine (Sun et al. 2008)., Authored: D'Eustachio, P, 2009-08-20, Edited: D'Eustachio, P, 2009-08-20, Reviewed: Hannun, YA, Luberto, C, 2009-11-18, Reviewed: Jassal, B, 2009-08-20
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ceramide + H2O <=> stearate + sphingosine [endoplasmic reticulum]
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3.5.1.23
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