Source:http://www.reactome.org/biopax/48887BiochemicalReaction4588
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At the late endosome membrane, myotubularin (MTM1), myotubularin-related protein 2 (MTMR2), myotubularin-related protein 4 (MTMR4), and myotubularin-related protein 7 (MTMR7) dephosphorylate phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) to phosphatidylinositol 5-phosphate (PI5P).<br><br>The following lists the above proteins with their corresponding literature references: MTM1 (Cao et al. 2007, Cao et al. 2008, Tsujita et al. 2004, Tronchere et al. 2004), MTMR2 (Cao et al. 2008), MTMR4 (Lorenzo et al. 2006), and MTMR7 (Mochizuki & Majerus 2003, Lorenzo et al. 2006).,
Authored: Williams, MG, 2011-10-18,
Edited: Williams, MG, 2011-08-12,
Reviewed: Wakelam, Michael, 2012-05-14
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| biopax3:xref |
http://identifiers.org/pubmed/12890864,
http://identifiers.org/pubmed/14660569,
http://identifiers.org/pubmed/14722070,
http://identifiers.org/pubmed/16787938,
http://identifiers.org/pubmed/17651088,
http://identifiers.org/pubmed/18524850,
urn:biopax:UnificationXref:REACTOME DATABASE ID_1676065,
urn:biopax:UnificationXref:REACTOME_REACT_121325_1
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PI(3,5)P2 is dephosphorylated to PI5P by MTM[3] at the late endosome membrane
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