Source:http://www.reactome.org/biopax/48887BiochemicalReaction4572
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At the plasma membrane, phosphatidylinositol-5-phosphate 4-kinase type-2 alpha (PIP4K2A) and beta (PIP4K2B) homodimers and heterodimers (Clarke et al. 2010) phosphorylate phosphatidylinositol 5-phosphate (PI5P) to phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2).<br><br>The following lists the above proteins with their corresponding literature references: PIP4K2A (Rameh et al. 1997, Clarke et al. 2008) and PIP4K2B (Rameh et al. 1997).,
Authored: Williams, MG, 2011-10-18,
Edited: Williams, MG, 2011-08-12,
Reviewed: Wakelam, Michael, 2012-05-14
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PI5P is phosphorylated to PI(4,5)P2 by PIP4K2A/B at the plasma membrane
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2.7.1.149
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