Source:http://www.reactome.org/biopax/48887BiochemicalReaction4510
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At the endoplasmic reticulum (ER) membrane, phosphatidylinositol (PI) is hydrolyzed, and has one of its acyl chains cleaved off, by cytosolic phospholipase A2 delta/epsilon (PLA2G4D/E) Ghomashchi et al. 2010). This produces 2-acyl lysophosphatidylinositol (LPI). Cytosolic phospholipase A2 enzymes show not only PLA2 hydrolyzing activity to form the 1-acyl lysophospholipid but also have a degree of PLA1 activity, producing a 2-acyl lysophospholipid.,
Authored: Williams, MG, 2011-09-14,
Edited: Williams, MG, 2011-08-12
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PI is hydrolyzed to 2-acyl LPI by PLA2[13]
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3.1.1.32
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