Source:http://www.reactome.org/biopax/48887BiochemicalReaction4487
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At the endoplasmic reticulum (ER) membrane, phosphatidylcholine (PC) is hydrolysed, and has one of its acyl chains cleaved off, by cytosolic phospholipase A2 alpha/beta/delta/epsilon/zeta (PLA2G4A/B/D/E/F) (Ghomashchi et al. 2010). This produces 2-acyl lysophosphatidylcholine (LPC). Cytosolic phospholipase A2 enzymes show not only PLA2 hydrolysing activity to form the 1-acyl lysophospholipid but also have a degree of PLA1 activity, producing a 2-acyl lysophospholipid.,
Authored: Williams, MG, 2011-09-14,
Edited: Williams, MG, 2011-08-12
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PC is hydrolysed to 2-acyl LPC by PLA2[7]
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3.1.1.32
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