Source:http://www.reactome.org/biopax/48887BiochemicalReaction4426
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Authored: Jassal, B, 2008-10-01 13:18:42,
Edited: Jassal, B, 2008-05-19 12:57:01,
Edited: Jassal, B, 2008-05-28 09:06:10,
Reviewed: D'Eustachio, P, 2008-05-28 08:30:54,
To be functionally active, vitamin D is required to be dihydroxylated. The first hydroxylation at position 25 is carried out by vitamin D 25-hydroxylase (CYP2R1) in the liver, forming calcidiol.
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25-Hydroxylation of vitamin D3 in liver
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