Source:http://www.reactome.org/biopax/48887BiochemicalReaction4400
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
17-Hydroxypregnenolone and NAD+ react to form pregn-5-ene-3,20-dione-17-ol and NADH + H+. This reaction is catalyzed by the 3 beta-hydroxysteroid activity of 3-beta-hydroxysteroid dehydrogenase/isomerase (HSD3B) enzyme associated with the endoplasmic reticulum membrane. The active form of the enzyme is a homodimer. The enzyme occurs in two isoforms that are similar in their biochemical properties but differ in their tissue expression: type I (HSD3B1) is found in placenta and skin, while type II (HSD3B2) is found in the adrenal glands and gonads.,
Authored: Jassal, B, 2008-10-01 13:18:42,
Edited: Jassal, B, 2007-04-20 21:09:56,
Reviewed: D'Eustachio, P, 2007-04-20 21:11:21
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
17-hydroxypregnenolone + NAD+ => pregn-5-ene-3,20-dione-17-ol + NADH + H+
|
| biopax3:name |
17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol
|
| biopax3:eCNumber |
1.1.1.145
|
| biopax3:left | |
| biopax3:right |