Source:http://www.reactome.org/biopax/48887BiochemicalReaction4376
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Authored: D'Eustachio, P, 2007-02-27 21:49:11,
Cholest-5-ene-3beta,7alpha,27-triol and NAD+ react to form 4-cholesten-7alpha,27-diol-3-one and NADH + H+, in a reaction catalyzed by HSD3B7 (3 beta-hydroxysteroid dehydrogenase type 7) in the endoplasmic reticulum membrane. Its function in vivo has been confirmed in studies of patients with defects in bile acid synthesis (Schwarz et al. 2000).,
Edited: D'Eustachio, P, 2007-02-27 21:49:11,
Reviewed: D'Eustachio, P, 2007-04-30 14:43:26
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Cholest-5-ene-3beta,7alpha,27-triol + NAD+ => 4-cholesten-7alpha,27-diol-3-one +NADH + H+
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Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one
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1.1.1.145
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