Source:http://www.reactome.org/biopax/48887BiochemicalReaction4373
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27-hydroxycholesterol is transported from the mitochondrial matrix to the extracellular space. In humans, this event is the major source of 27-hydroxycholesterol in the blood and is the means by which the molecule, generated from cholesterol in a variety of cell types, notably macrophages, is transported to the liver for conversion to bile acids and bile salts (Babiker et al. 1999; Bjorkhem et al. 1994). While transport proteins are likely to play a role in this process, the relevant proteins have not been identified.,
Authored: D'Eustachio, P, 2007-02-27 21:49:11,
Edited: D'Eustachio, P, 2007-02-27 21:49:11,
Reviewed: D'Eustachio, P, 2007-04-30 14:43:26
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Efflux of 27-hydroxycholesterol
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